This is arguably the most interferon-free combination available for the treatment of HCV genotypes 1 to 6. For patients suffering from genotype 3, Epclusa provides a single-pill option which can be taken without combining with ribavirin. If the patient has severe cirrhosis, the regimen can be taken with ribavirin but not in cases involving compensated cirrhosis. Eplusa is said to remove the Hep-C virus